Pinella Nutramedix 30ml

Pinella 30 ml

Solves problems with toxin overload:
- brain
- spinal cord

General description

Pinella - Brain & Nerve Cleanse is an herbal extract from Pimpinella anisum. It has been used by local people for hundreds of years. Pinella is an integral component of the Lyme disease protocol developed by Dr. William Lee Cowden. Dr. Cowden and other healthcare workers found it very effective in eliminating both human-origin toxins and biotoxins from the brain, spinal cord, and peripheral nerves. Both patients and healthcare workers also report that significant reduction of brain fog often occurs even after just one dose.

Reported medical properties

• analgesic
• soothing
• antibacterial
• anticonvulsant
• antifungal
• antimicrobial
• antioxidant
• antiviral
• aphrodisiac
• aromatic
• carminative
• diaphoretic
• disinfectant
• diuretic
• against painful menstruation
• galactagogue
• hypoglycemic
• hypolipidemic
• muscle relaxant
• calming
• stimulating

Product research
(information from recognized scientific papers - sources in English)

ANTI-INFLAMMATORY - IN VIVO
Establishment of the Potential Anti-inflammatory Effect of the product known as Pinella. The study demonstrated that Pinella had a marked anti-inflammatory effect and was 64% as effective as Feldene, a non-steroidal anti-inflammatory drug also known as PIROXICAM. University of Guayaquil, Department of Chemical Sciences, Guayaquil, Ecuador (2005).

ACUTE ORAL TOXICITY TEST - IN VIVO
An acute Oral toxicity study was conducted by the University of Guayaquil, Ecuador concluding that Pinella did not produce toxic effects, thus the product is considered practically innocuous for humans when administered in the acute form. Therefore; studies of acute toxicity at higher doses in humans are not necessary.
Full article

Medical conditions
(information from recognized scientific papers - sources in English)

CANCER
Al Salhi, M. S., Devanesan, S., Alfuraydi, A. A., Vishnubalaji, R., Munusamy, M. A., Murugan, K., ... & Benelli, G. (2016). Green synthesis of silver nanoparticles using Pimpinella anisum seeds: antimicrobial activity and cytotoxicity on human neonatal skin stromal cells and colon cancer cells. International Journal of Nanomedicine, 11, 4439.
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Kadan, S., Rayan, M., & Rayan, A. (2013). Anticancer activity of anise (Pimpinella anisum L.) seed extract. The Open Nutraceuticals Journal, 6(1).

DIABETES
Shobha, R. I., Rajeshwari, C. U., & Andallu, B. (2013). Anti-peroxidative and anti-diabetic activities of aniseeds (Pimpinella anisum L.) and identification of bioactive compounds. American Journal of Phytomedicine and Clinical Therapeutics, 1(5), 516-527.
Full article

Medical properties
(information from recognized scientific papers - sources in English)

ANTIBACTERIAL
Foroughi, A., Pournaghi, P., Tahvilian, R., Zangeneh, M. M., Zangeneh, A., & Moradi, R. (2016). Assessment of chemical composition and antibacterial effects of Anethole-rich hydroalcoholic extract of Pimpinella anisum. International Journal of Pharmaceutical and Clinical Research, 8(11), 1459-1463.
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Al Maofari, A., El Hajjaji, S., Debbab, A., Zaydoun, S., Ouaki, B., Charof, R., ... & Mosaddak, M. (2013). Chemical composition and antibacterial properties of essential oils of Pimpinella Anisum L. growing in Morocco and Yemen. Scientific Study & Research. Chemistry & Chemical Engineering, Biotechnology, Food Industry, 14(1), 11.
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Al-Bayati, F. A. (2008). Synergistic antibacterial activity between Thymus vulgaris and Pimpinella anisum essential oils and methanol extracts. Journal of Ethnopharmacology, 116(3), 403-406.
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Akhtar, A., Deshmukh, A. A., Bhonsle, A. V., Kshirsagar, P. M., & Kolekar, M. A. (2008). In vitro antibacterial activity of Pimpinella anisum fruit extracts against some pathogenic bacteria. Veterinary World, 1(9), 272-274.
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ANTIOXIDANT
Tavallali, V., Rahmati, S., & Bahmanzadegan, A. (2017). Antioxidant activity, polyphenolic contents and essential oil composition of Pimpinella anisum L. as affected by zinc fertilizer. Journal of the Science of Food and Agriculture, 97(14), 4883-4889.
Full article

Jamshidzadeh, A., Heidari, R., Razmjou, M., Karimi, F., Moein, M. R., Farshad, O., ... & Shayesteh, M. R. H. (2015). An in vivo and in vitro investigation on hepatoprotective effects of Pimpinella anisum seed essential oil and extracts against carbon tetrachloride-induced toxicity. Iranian Journal of Basic Medical Sciences, 18(2), 205.
Full article

Singh, G., Kapoor, I. P. S., Singh, P., de Heluani, C. S., & Catalan, C. A. N. (2008). Chemical composition and antioxidant potential of essential oil and oleoresins from anise seeds (Pimpinella anisum L.). International Journal of Essential Oil Therapeutics, 2(3), 122-130.
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Gülçın, İ., Oktay, M., Kıreçcı, E., & Küfrevıoǧlu, Ö. İ. (2003). Screening of antioxidant and antimicrobial activities of anise (Pimpinella anisum L.) seed extracts. Food Chemistry, 83(3), 371-382.
Full article

ANTICONVULSANT
Karimzadeh, F., Hosseini, M., Mangeng, D., Alavi, H., Hassanzadeh, G. R., Bayat, M., ... & Gorji, A. (2012). Anticonvulsant and neuroprotective effects of Pimpinella anisum in rat brain. BMC Complementary and Alternative Medicine, 12(1), 76.
Full article

Pourgholami, M. H., Majzoob, S., Javadi, M., Kamalinejad, M., Fanaee, G. H. R., & Sayyah, M. (1999). The fruit essential oil of Pimpinella anisum exerts anticonvulsant effects in mice. Journal of Ethnopharmacology, 66(2), 211-215.
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ANTIFUNGAL
Yazdani, D., Rezazadeh, S. H., Amin, G. H., Abidin, Z., Shahnazi, S., & Jamalifar, H. (2009). Antifungal activity of dried extracts of anise (Pimpinella anisum L.) and star anise (Illicium verum Hook. f.) against dermatophyte and saprophyte fungi. Journal of Medicinal Plants, 1(29), 24-29.
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Sharifi, R., Kiani, H., Farzaneh, M., & Ahmadzadeh, M. (2008). Chemical composition of essential oils of Iranian Pimpinella anisum L. and Foeniculum vulgare miller and their antifungal activity against postharvest pathogens. Journal of Essential Oil Bearing Plants, 11(5), 514-522.
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Kosalec, I., Pepeljnjak, S., & Kuštrak, D. (2005). Antifungal activity of fluid extract and essential oil from anise fruits (Pimpinella anisum L., Apiaceae). Acta Pharmaceutica, 55(4), 377-385.
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Shukla, H. S., & Tripathi, S. G. (1987). Antifungal substance in the essential oil of anise (Pimpinella anisum L.). Agricultural and Biological Chemistry, 51(7), 1991-1993.
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ANTIMICROBIAL
Mohamed, H. S. A. A., Abdelgadir, W. S., & Almagboul, A. Z. (2015). In vitro antimicrobial activity of Anise seed (Pimpinella anisum L.). International Journal of Advanced Research, 3(1), 359-367.
Full article

Mohammed, M. J. (2009). Isolation and identification of Anethole from Pimpinella anisum L. fruit oil. An antimicrobial study. J Pharma Res 2009; 915, 919.
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Gende, L. B., Maggi, M. D., Fritz, R., Eguaras, M. J., Bailac, P. N., & Ponzi, M. I. (2009). Antimicrobial activity of Pimpinella anisum and Foeniculum vulgare essential oils against Paenibacillus larvae. Journal of Essential Oil Research, 21(1), 91-93.
Full article

ANTIVIRAL
Lee, J. B., Yamagishi, C., Hayashi, K., & Hayashi, T. (2011). Antiviral and immunostimulating effects of lignin-carbohydrate-protein complexes from Pimpinella anisum. Bioscience, Biotechnology, and Biochemistry, 75(3), 459-465.
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Shukla, H. S., Dubey, P., & Chaturvedi, R. V. (1989). Antiviral properties of essential oils of Foeniculum vulgare and Pimpinella anisum L. Agronomie, 9(3), 277-279.
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HEPATOPROTECTIVE
Cengiz, N., Ozbek, H., & Him, A. (2008). Hepatoprotective effects of Pimpinella anisum seed extract in rats. Pharmacologyonline, 3, 870-874.
Full article

RELAXANT
Tirapelli, C. R., de Andrade, C. R., Cassano, A. O., De Souza, F. A., Ambrosio, S. R., da Costa, F. B., & de Oliveira, A. M. (2007). Antispasmodic and relaxant effects of the hydroalcoholic extract of Pimpinella anisum (Apiaceae) on rat anococcygeus smooth muscle. Journal of Ethnopharmacology, 110(1), 23-29.
Full article

Boskabady, M. H., & Ramazani-Assari, M. (2001). Relaxant effect of Pimpinella anisum on isolated guinea pig tracheal chains and its possible mechanism(s). Journal of Ethnopharmacology, 74(1), 83-88.
Full article

MISCELLANEOUS PROPERTIES
Shojaii, A., & Abdollahi Fard, M. (2012). Review of pharmacological properties and chemical constituents of Pimpinella anisum. ISRN Pharmaceutics, 2012.
Full article

VIDEO
(English version)

Customer reviews

"This is the best remedy I have taken to clear 'brain fog.' I could feel immediate effects as soon as I started using it!" - K.F.

"It worked wonderfully for me, now I am able to express myself better and my sleep has improved." - J.M.

Dosage instructions

General detox: 10 drops in 120 ml of water 1-2 times a day.

Mild toxin overload: 10 drops 3-4 times a day. Can be taken several times a day as needed.

Moderate and severe toxin overload, Herxheimer reaction (healing crisis): 10 drops every 15 minutes in 120 ml of water until symptoms subside.

You can also pour 2 full droppers (about 60 drops) into 480 ml of water. Sip over 2 hours, repeat until symptoms subside.

Note: It is recommended to use the product with 10 drops of Burbur or Prasley for a more complete elimination of toxins from the body (dose in the same water as Pinella).

Safety information

An acute oral toxicity study was conducted by the University of Guayaquil, Ecuador, which concluded that Pinella did not cause toxic effects, therefore the product is considered practically harmless to humans when administered in acute form. Consequently, studies of acute toxicity at higher doses in humans are not necessary.

Product safety information Manufacturer information